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Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis

doi: 10.1111/j.1471-4159.1992.tb09439.x

Our findings uncover a previously unrecognised pro-necroptotic signalling axis by demonstrating that STK38 activates RIPK1 to accelerate cell death

[DOI] [PubMed] [Google Scholar] 345.Lopez-Otin, C

What has been lacking is an integrated and quantitative understanding of the kinetics of APAP metabolism, of how APAP dosage affects NAPQI synthesis and GSH concentrations in the liver, of how NAC stimulates the synthesis of GSH, and of how the dosage and timing of NAC affect detoxification of NAPQI