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Each type of EDS has its own diagnostic criteria that describe the set of features associated with that type

In HIF-1 knockout mice, the absence of HIF-1 signaling results in defective epigenetic programming and impaired production of proinflammatory cytokines (180)

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Therefore, in this study, we attempted to elaborate and summarize the linkage of cuproptosis and key genes regulating cuproptosis to the pathological mechanisms of RA and their effects on a variety of immune cells

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