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The different response to the increased oxygen concentration in cancer cells, compared to healthy cells, may be linked to several mechanisms: A maladaptive response to hyperoxia, as well as to modification in adenosine pathways able to trigger anticancer effects of T cells and NK cells [84,85]

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doi:10.1161/JAHA.117.005466 Di Minno MN, Ambrosino P, Ambrosini F, Tremoli E, Di Minno G, Dentali F

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Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver
