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It has been suggested that pro-inflammatory cytokines can induce stress-induced neuroendocrine and central neurotransmitter changes similar to those in patients with depression [147], and IFN-a immunotherapy has been shown to induce depression [148,149]

TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading

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Twenty-four-weeks of LC supplementation alone did not affect muscle strength in healthy aged women [15], but significantly increased muscle mass, improved physical effort tolerance and cognitive function in centenarians [14]