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Blood Sugar Regulation: MTHFR mutations can impact insulin sensitivity and glucose metabolism

This could be a key mechanism by which IGFBP-3, IGFBP-5 and possibly other IGFBPs can regulate the balance between cell death and survival in response to certain cancer therapies
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Also, thermal processing affects T-cell reactivity, as cooked extracts increase IgE reactivity and reduce Treg levels compared to raw extracts, highlighting the immune-modulatory effects of cooking [130]
