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Culture synchronization was induced by growth in 14-h-light/10-h-dark cycles or 12-h-light/12-h-dark cycles as described
Periodically, the FDA updates these forms to enhance their usability and incorporate relevant content to help sponsors and reviewers
doi: 10.1089/sur.2017.089
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Patients with NAFLD exhibit an increase in the activity of CYP2E1 and a diminution of 1.9 and 3.1 times in the activity of CYP3A4 in NAFLD and Non-alcoholic Steatohepatitis (NASH), respectively [80,81]
