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Lipid accumulation in hepatocytes can affect mitochondrial function, ER membrane fluidity and calcium ion homeostasis
ZhaoX-YZhongQ-HTanHWYanRWangX-YCaiN-Let al
680,681,682 Small molecules targeting ferroptosis by regulating the ACSL4-LOX axis Lipid peroxidation is a hallmark of ferroptosis, and lipid-metabolizing enzymes such as ACSL4 and LOX contribute to ferroptosis
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