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Description
elegans encodes the ortholog of the mammalian GCLM regulatory subunit [68,75]
National Institute for Biological Standards and Control: A.J
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Notably, further studies discovered an inducible GPX4 transcript-variant (iGPX4) in NAFLD conditions, and suppression of iGPX4 by siRNA-iGPX4 significantly alleviated oxidative stress and cellular damage by impairing ferroptosis
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