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Others can reduce very gradually and slowly and still experience symptoms long after stopping

A 2025 Phase 3 trial in people with obesity and knee osteoarthritis showed nearly 29% weight loss plus meaningful pain relief

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Seven reported feeling relief for more than six monthsmoderately encouraging, but hardly the large-scale human trial typically required for drug approval

Working with a trained counselor or support group can help you reduce stress, maintain positive mental health, and manage your illness effectively.