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In the SKOV-3 cell line extending the BSO pretreatment period to 48 h from 24 h marginally reduced the cytotoxicity of cisplatin, whereas the cytotoxicity of the other three drugs remained similar to that observed after 24 h BSO pretreatment
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Anabolic Signaling: The released GH stimulates the liver to produce IGF-1, which activates the mTORC1 pathway in muscle (protein synthesis) and the Runx2 pathway in bone (osteoblast differentiation)
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