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Potential Side Effects: Gastrointestinal effects (most common): nausea, vomiting, diarrhea, constipation, abdominal paintypically mild to moderate and decreasing with gradual dose escalation [1] [3]

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The neuronal pathological changes were also observed in the acquired digital images saved as uncompressed 24-bit RGB TIFF files in the software program AnalySIS (Olympus Soft Imaging System GmbH, Mnster, Germany) performing quantitative analysis of neuronal damage in the karyopyknotic areas

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