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Astrocyteneuron lactate shuttle: mechanisms, signaling functions and controversies Beyond binding to postsynaptic membrane glutamate receptors to generate postsynaptic currents or initiate cell signaling pathways, glutamate released into the synaptic space by the neuronal presynaptic membrane can also be taken up by astrocytes through glutamate transporters

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Additionally, glutamine metabolism supports the mitochondrial functions and cellular redox metabolic capacity of AML cells, resulting in the adverse prognosis of AML patients carrying the FLT3-ITD mutation

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To assess the effects of mitochondrial transplantation on the MMP of neuronal cells, SH-SY5Y cells were seeded in black 96-well plates at a density of 1.5 10^ 4 cells/well