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Breakpoint: Based on pharmacokinetic studies of enrofloxacin in dogs and cats after a single oral administration of 2.5 mg enrofloxacin/kg BW (i.e
According to NICE guidance and standard UK clinical practice, patients with confirmed B12 deficiency and neurological symptoms typically require initial treatment with hydroxocobalamin injections

Situations or conditions that can cause vitamin B12 deficiency include: You are more likely to develop vitamin B12 deficiency if you have one or more of the following risk factors: Left untreated, vitamin B12 deficiency can cause lasting side effects that affect your nervous system and brain

Treatment frequency depends on your condition

Community sources describe bedtime dosing to minimize impact Facial flushing within 30-60 minutes, lasts 1-2 hours Appetite suppression community sources describe reductions exceeding 50% during the loading phase Libido increase pronounced
