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Description
This overgrowth leads to fermentation, gas production, inflammation, and symptoms that closely mirror IBS

doi: 10.1111/apha.13850, 49

Glycogen synthase kinase-3 haploinsufficiency mimics the behavioral and molecular effects of lithium

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What ensues is the breakdown of collagen and proteoglycans, leading to cartilage and bone destruction, and joint erosion
