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These observations raise an intriguing possibility that insults in HSCs over the lifespan are a driver of maladaptive trained immunity, resulting in aging-associated inflammation and functional decline of distant tissues
doi: 10.1007/s10741-018-9716-x 33
It functions as an antioxidant, and it plays a critical role in detoxification and preventing cellular damage
& Jungheim, E
The percentage of oxidation at each cysteine site was quantified by calculating the ratio of the levels of reversibly oxidized cysteine and total cysteine, as determined by CPT labeling and TMT-based MS quantification
