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In advanced cases of PDR, the financial burden is further compounded by surgical interventions such as vitrectomy, which carry not only higher costs but also increased risks and variable outcomes depending on systemic comorbidities and the severity of retinal damage
Biochimica et Biophysica Acta - Molecular Cell Research, 1863(10), 24222435 Garolla, A., Maiorino, M., Roverato, A., Roveri, A., Ursini, F., & Foresta, C
It is also important to recognise that targeted replacement of murine Apoe with human APOE alleles may itself influence pathological outcomes
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