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Most of what is known today about the role of ferroptosis is derived from studies using ferroptosis inhibitors such as the RTAs liproxstatin-1 and ferrostatin-1, which have been shown to protect from IRI in a wide range of tissue contexts [6,34,188,[501], [502], [503], [504], [505]]

(2007) The alternative pathway of glutathione degradation is mediated by a novel protein complex involving three new genes in Saccharomyces cerevisiae

cuspidatum root extract, had a methylglyoxal-trapping action (IC 50 = 0.41 mM lower than the reference aminoguanidine IC 50 = 1.05 mM) and prevented the development of advanced glycation end products formed from methylglyoxal

Niles, J