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Description
Tanshinone IIA (TIIA) enhances NRF2 binding and transcriptional activation at the promoters of target transporter proteins BSEP and NTCP through TET2-mediated demethylation of NRF2
Figure 5 GABA shunt is mainly composed of three enzymes: GAD, GABA-T, and SSDHA (Bouch et al., 2003)

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The modified peptide was deprotected/cleaved and macrocyclized as described above, followed by RP-HPLC purification and in vacuo lyophilization

Complexed and ligand-free high-resolution structures of urate oxidase (Uox) from Aspergillus flavus: a reassignment of the active-site binding mode