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We have better news about the other two things: in-vitro data shows that MAP can boost collagen synthesis similar to AA (though in the case of AA it's proven in-vivo) and even better, MAP is proven to work as a skin brightener in-vivo (on real people)

Inflammation and Thrombosis in Essential Thrombocythemia and Polycythemia Vera: Different Role of C-Reactive Protein and Pentraxin 3

3a) confirms that OCTN2 undergoes large rocker-switch like rearrangements, mediated by a relatively rigid N-terminal bundle together with a more flexible C-terminal bundle