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Secondly, in order to preserve residual mitochondrial bioenergetics and positively regulate the body homeostasis/adaptation capacities of these patients, the manuscript will put forward an innovative therapeutic view for the management of the disease, based on a diet with a moderate intake of carbohydrates and enriched in proteins, the practice of exercises of suitable type and intensity and a potential use of dietary supplements (Table 1)

Acetyl-L-carnitine should be taken continuously over a minimum period of 3 to 6 months, to ensure the optimal build-up of vital substances

Additionally, the LNP surface charge significantly impacts biodistribution and mRNA delivery efficiency

Delivers 1,000 mg of Lcarnitine to support blood glucose and glucose metabolism (for individuals within the normal range)*

C.SchuM.CarrireF.GeerlofA.CanaanS