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Assessments of fatigue were performed by all patients at the first time point during the period of standard HD, and within 2 weeks before commencement of EHD system (M0) using questionnaire asking How did you feel tired in the previous HD day, and the next day of HD? And NRS (HD and HD-free days) were repeatedly asked at the 1st month (M1), 3rd months (M3), 6th months (M6), and 12th months (M12) after commencement of E-HD system

In the absence of Opa1, Te cells remain able to engage FAO in vitro, suggesting that although both FAO and mitochondrial fusion regulate Tm cell functionality, they may not necessarily be directly connected and instead reflect two independent pathways that are important for Tm cell recall (71, 161)

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Generally, SCLC and NSCLC have low 5-year survival rates, 7% and 21%, respectively [154], and there are no druggable or effective cell-surface markers for LCC or SCLC

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