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Multiple sclerosis Multiple sclerosis is an autoimmune disease of unknown etiology that is characterized by the progressive destruction of myelin and nerve fibers in the central nervous system, causing neurological symptoms in affected individuals (85)

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Cataplexy and a significant reduction in orexigenic neurons, which are responsible for the release of orexin-A and orexin-B neuropeptides, are the hallmarks of type 1 narcolepsy