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Description
Glutaminase converts glutamine into glutamate, which is further converted to -ketoglutarate, a key metabolite for replenishing TCA cycle intermediates, especially in cells undergoing aerobic glycolysis (known as the Warburg effect) 2
[DOI] [PubMed] [Google Scholar] 62.Fakhraei Lahiji S., Seo S.H., Kim S., Dangol M., Shim J., Li C.G., Ma Y., Lee C., Kang G., Yang H., et al
It is composed of three amino acidsglutamine, cysteine, and glycine
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found that AGK belonged to a subunit of the TIM22 complex that facilitates the transport of metabolite carriers into the IMM
