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[PUBMED Abstract] Stam RW, Schneider P, de Lorenzo P, et al.: Prognostic significance of high-level FLT3 expression in MLL-rearranged infant acute lymphoblastic leukemia

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-KG is a key modulator of the hypoxic response Prolyl-hydroxylases PHD13 are 2-OGDD enzymes critical in the regulation of the transcription factor HIF-1, a master regulator of O 2 homeostasis

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The inability of 5-cholesten-3-one to serve as substrate for the bacterial ketosteroid isomerase was noted in the original publication (Talalay and Wang, 1955), and the purified mammalian GST A3-3 from different sources also lack detectable activity with this steroid (unpublished work in our laboratory)

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