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J., Sterk, P
Interestingly, ALC is a transcriptional inducer of the mGluR2 gene in the prefrontal cortex, hippocampus, and spinal circuits, thus modulating glutamatergic activity [95, 165, 168, 169]
Patients who remain at lower doses (2.55 mg) due to side effect concerns may not achieve optimal therapeutic benefit
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He W, Lam TK, Obici S, Rossetti L: Molecular disruption of hypothalamic nutrient sensing induces obesity