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Description
There is no published pharmacokinetic study confirming that sublingual SLU-PP-332 produces serum concentrations comparable to IP injection in mice
Furthermore, elevated levels of phosphorylated serine 65 of ubiquitin and PRKN have been observed, which are associated with the phosphorylation of ubiquitin by PINK1 at the outer mitochondrial membrane (OMM), have been identified in postmortem PD brains (107)

They come from the same gene family but arise by completely different processes natural splicing versus deliberate protein engineering and are studied for different proposed roles

[DOI] [PubMed] [Google Scholar] 108.Achkor H, Daz M, Fernndez MR, Biosca JA, Pars X, Martnez MC

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