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The potential hepatotoxicity of herbal products has also been recognized in recent years (Stickel and Shouval, 2015)

Simultaneous homotopic transplantation of fetal dopaminergic progenitors into the ventral midbrain of 6-OHDA-lesioned mice together with ChABC injected into the nigrostriatal bundle did not affect graft survival, but significantly enhanced axonal growth along the nigrostriatal pathway and increased reinnervation of the striatum compared to untreated grafted controls (Kauhausen et al., 2015)

2021;42, article 101668 doi: 10.1016/j.redox.2020.101668

10.1021/acssynbio.2c00570

Further, the EXODIAB biobank identified upregulation of haemostasis and complement cascade-associated proteins in islets from prediabetic donors compared with control donors, while these proteins were downregulated in overt diabetes [24]