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The main mechanisms include stimulating the expression of follicle-related growth factors, dilating scalp blood vessels and improving microcirculation, boosting the differentiation and proliferation of hair follicle epithelial cells, and activating the Wnt/-Catenin signaling pathway and its key proteins (Scheme 2)

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Peroxisome proliferator-activated receptor delta (PPAR) agonists, e.g