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Drug approval takes years, moving through phased clinical trials that grow from just a few hundred participants to thousands

doi: 10.1503/jpn.230046

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For example, a proportion of patients with Parkinson's disease develop dementia, Cognitive impairment also occurs in the Parkinson-plus syndromes of progressive supranuclear palsy and corticobasal degeneration (and the same underlying pathology may cause the clinical syndromes of frontotemporal lobar degeneration)
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