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Abbreviations ALL: acute lymphoblastic leukemia CC: cancer cells CNS: central nervous system COX: cyclooxygenase DHA: docosahexaenoic acid EC: esophageal cancer EGCG: epigallocatechin gallate EPA: eicosapentaenoic acid IL: interleukin ITC: Isothiocyanate KD: ketogenic diet MUFA: monounsaturated fatty acids PUFA: polyunsaturated fatty acids SFA: saturated fatty acids TNF: tumor necrosis factor UGI: upper gastrointestinal Declarations Acknowledgement NPN would like to thank Mahidol University, Thailand, for providing Global Talent position

203,204,205,206 Studies have shown that FMT in combination with probiotic therapy at a ratio of 9:1 can significantly reduce intestinal barrier damage, decrease the levels of TNF- and IL-6 in colon tissue, and alleviate UC symptoms

The effort involved limits practical application for most users

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