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Nature Neuroscience, 27 (10), 19341944

Researchers often develop comprehensive models by integrating diverse data sources, including clinical assessments, psychological evaluations, and biomarkers

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It should be noted, however, that these are few and preliminary studies that, on the one hand, provide valuable and promising data, but on the other hand, the results are limited and have not yet been sufficiently confirmed

Add to that our increasingly fine-tuned understanding of some of the regulated ROS generating systems that produce a significant fraction of the oxidants to be sensed, and it is clear that we CAN begin to construct models for these complex biological networks, but that continued research will be required in order to better understand the redox chemistry underlying vital cell processes