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Researched applications In the published preclinical and clinical literature the effects of Cagrilintide are documented in the following areas: Obesity (stand-alone) , Phase 2 data (Lau 2021, 10.8 % at 4.5 mg) Obesity + Semaglutide (CagriSema) , Phase 3 REDEFINE 1 (25.3 %) T2DM + obesity , Phase 3 REDEFINE 2 Cardiovascular prevention , Phase 3 REDEFINE 3 (n ~ 7000) MASLD/MASH , exploratory in Phase 2 Type 2 diabetes (monotherapy) , preclinical data Prediabetes , exploratory plans Science & studies 4.1 Key publications Lau D.C.W., Erichsen L., Francisco A.M., et al

Improved cognitive function

Data from preclinical models of glutathione deficiency, supported by magnetic resonance spectroscopy studies, show increased glutathione levels in the brains of people who receive sulforaphane

While most people produce sufficient IF, a condition known as atrophic gastritis, affecting 1030 percent of people over 60 years of age, 5 can cause intrinsic factor deficiency, which in turn can cause B12 deficiency due to malabsorption

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