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doi: 10.1146/annurev.neuro.27.070203.144244

10.1016/S1570-0232(03)00399-4 Summary Keywords acetaminophen, reactive metabolite, covalent binding, glutathione S -transferase, bottom-up proteomics, data-dependent acquisition, high-resolution tandem mass spectrometry, multiple reaction monitoring Citation Geib T, Lento C, Wilson DJ and Sleno L (2019) Liquid Chromatography-Tandem Mass Spectrometry Analysis of Acetaminophen Covalent Binding to Glutathione S -Transferases

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However, genetic studies cannot provide the same fine-tuning and evaluation of dose-dependency and dosage scheduling that is possible with pharmacological agents

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