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Once exposed to room temperature for extended periods, the vial should not be returned to refrigerated storage and used beyond the 21-day window

Since valproate products may produce CNS depression, especially when combined with another CNS depressant (e.g., alcohol), patients should be advised not to engage in hazardous activities, such as driving an automobile or operating dangerous machinery, until it is known that they do not become drowsy from the drug

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3 (July 2018): 71318

There are other examples of different nanocarriers administered by intrathecal injection, including polymer-based nanocomplexes [99102] and inorganic nanocarriers [103]