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A recent work has provided evidence that the formation of the epimer from zearalenone proceeds with 3-keto-DON as an intermediate (Hassan et al., 2017)
Elevated serum levels of soluble CD44 can identify a subgroup of patients with early B-cell chronic lymphocytic leukemia who are at high risk of disease progression

Effects of Alpha-Lipoic Acid Supplementation on Inflammatory Biomarkers and Matrix Metalloproteinase-3 in Rheumatoid Arthritis Patients
Such approaches have started to be employed (e.g., using Nrf2-knockout mice to confirm a compounds effects are via Nrf2)

Challenges in chondrocyte-based therapies remain, including limited scalability owing to their proliferative capacity in vitro and the risk of dedifferentiation during expansion 50,51