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Stimulates the antioxidant effect in order to reduce oxidative stress treatment

doi: 10.1186/s13287-021-02161-8 111 PhinneyDGPittengerMF

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In this setting, toxic microbe products, including endotoxins (bacterial membrane lipopolysaccharides, LPS) of gram-negative bacteria and analogous molecules in the walls of gram-positive bacteria and fungi, dramatically activate mononuclear cells to release cytokines[156] that upregulate bradykinin B1 receptors[157,158], inducible NO synthase[159] and COX-2[160], which increase NO and prostaglandin E2

[10] Additionally, 5-HT3 receptors are present in the gastrointestinal tract, particularly in the vagal nerve terminals, where they may contribute to the transmission of emetogenic signals