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It is important to note that B12 levels should ideally be measured before commencing replacement therapy, as supplementation rapidly normalises biochemical markers, potentially obscuring the diagnosis
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Knockout of ferritin heavy chain 1 (FTH1) has been demonstrated to reduce NCOA4 levels by increasing free iron, which activates the HERC2-mediated degradation of NCOA4 (79,89)
Remember always to seek prenatal care and talk to your healthcare professionals about any additional support you might need during your pregnancy
