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Our findings revealed a network of interactions in which NTZ may be connected to various proteins critical for oxidative stress, inflammation, and apoptosis (Khayami et al., 2020

Structural analyses indicate that -amylase activity requires calcium ions to maintain structural integrity and is activated by chloride ions, and similarly, -glucosidase operates via a Koshland double displacement reaction mechanism (64)
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It has significant antioxidant and anti-inflammatory properties, suppressing the synthesis of important pro-inflammatory cytokines such as interleukin-6 (IL-6), interleukin-1 (IL-1), and tumor necrosis factors (TNFs) (25)

berghei transfections were accomplished by electroporation of purified schizonts using the Amaxa Nucleofector Technology (Lonza) as described previously ( pbgst - ko 1A and 1B , containing the tgdhfr/ts selectable marker, were selected with pyrimethamine as previously described ( pbgst - ko 2A and 2B , which contains the hdhfr selectable marker, were selected with WR99210 ( pbgst-ko 2A and 2B were done in parallel with a previously described plasmid targeting the pbmrp as a transfection control ( Integration of knockout plasmids was verified by Southern analysis of chromosomes separated by CHEF or FIGE
