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Patients are consequently at high risk for systemic thromboembolism, particularly ischemic stroke

[DOI] [PubMed] [Google Scholar] 211.Bello M.L., Nuccetelli M., Caccuri A.M., Stella L., Parker M.W., Rossjohn J., McKinstry W.J., Mozzi A.F., Federici G., Polizio F., et al

Consequently, the inactivation of GPX4, either through the inhibition of System Xc or the depletion of intracellular GSH, represents a classic experimental method for inducing ferroptosis