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Tissue sections were imaged under a microscope (DMi8, Leica Microsystems, Wetzlar, Germany, with a Hamamatsu Orca Flash 4 v3 sCMOS camera) where fluorescence was excited with a lumencor spectra X using 550 nm (secondary antibody Alexa Fluor 594), 470 nm (secondary antibody Alexa Fluor 488) or 385 nm (DAPI), and exposure time was held constant for each color channel regarding magnification and staining

B12 injections can lower elevated homocysteine levels, thereby reducing the risk of heart disease

In addition, microglia, astrocytes, endothelial cells, and peripheral immune cells release inflammatory cytokines and chemokines, causing a prolonged proinflammatory state of microglia, increasing the permeability of the BBB and facilitating the infiltration of immune cells into the CNS [13,14]

In the case of Lopez Bernal et al , they also assessed which variant each "case" contracted (e.g

doi: 10.1002/mds.22340