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Essential for hospital patients with gastrointestinal disorders, bowel surgery, alcoholism, or chronic illness

At the same time these astrocytes reduce expression of several key homoeostatic proteins such as glutamate transporters, glutamine synthetase, K ir 4.1 inward rectifying channels involved in K + buffering, and connexion 43 responsible for syncytial coupling

Cryptotanshinone protects against PCOS-induced damage of ovarian tissue via regulating oxidative stress, mitochondrial membrane potential, inflammation, and apoptosis via regulating ferroptosis

Meanwhile, mitochondrial dysfunction impairs ATP-dependent lysosomal and proteasomal functions, weakens the cellular self-clearing capacity, and thereby indirectly contributes to -syn accumulation

Egypt J Aquat Res 49:549554 Poupon R (2012) Ursodeoxycholic acid and bile-acid mimetics as therapeutic agents for cholestatic liver diseases: an overview of their mechanisms of action