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If you have sub-optimal levels with symptoms, its worth a trial of B12 even if your serum B12 levels are normal

CHS was added in case the protein needs cholesterol to be stable

Vegetarians and vegans need to be particularly vigilant since B12 only occurs naturally in animal products
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On the other hand, in very limited studies, protein restriction has been associated with a slower decline in eGFR in non-diabetics with CKD
Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses