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Neurochem Int 61:100107 Nasca C, Xenos D, Barone Y, Caruso A, Scaccianoce S, Matrisciano F, Battaglia G, Mathe AA, Pittaluga A, Lionetto L, Simmaco M, Nicoletti F (2013) l-Acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors

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Therefore, overlap with another form of anticoagulation with a faster onset, historically unfractionated or low molecular weight heparin, is required for the first 5 days and until the INR produced by warfarin therapy is in the therapeutic range for 2 consecutive days
