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Molecular analyses reveal that 5-amino-1MQ administration alters expression of key genes involved in epithelial-mesenchymal transition, including increased ZEB1 and SIRT1 expression alongside decreased TWIST and SERPIN1 levels

The authors declare no conflict of interest

doi: 10.1186/s13046-018-0673-y

For the analysis of aflatoxin exposure in hematic matrices, the detection of aflatoxin covalently bound to albumin (AF-Alb) via a lysine residue is the method of choice and the only validated biomarker for this fluid, with 1.42.3% of ingested AFB1 being converted to this compound (Gan et al

This bypasses the skin barrier that limits topical absorption, allowing higher concentrations to reach the dermis and deeper tissue layers