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These females are known as asymptomatic female carriers. Genetic testing is also available for sisters of girls with Rett syndrome who have an identified MECP2 mutation to determine if they are asymptomatic carriers of the disorder, which is an extremely rare possibility

Hewitt, Morgan C

It is found in high concentrations in tissues such as the heart, skeletal muscles, and brain

Moreover, their tolerance level isnt enough to handle the additional potency, and this can lead to cardiac arrest and death

159 However, two studies that compared the response of women with PCOS to that of healthy controls found that, while exercise did deliver many of the expected benefits to women with PCOS, it failed to alter the glucose-insulin dynamic in the body as a whole and in skeletal muscle, and it did not have the expected effect on fat burning