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Not well supported: High-quality, reproducible human trials demonstrating meaningful improvement in tendon/ligament healing time, re-injury rates, or function with these specific compoundsespecially as used in the wild (variable dosing, variable sourcing, variable diagnosis)

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Conflicts of Interest The authors declare that there are no conflict of interest

For instance, a 12-month randomized controlled trial involving older adults (ages 60 to 81) demonstrated a 1.1-kilogram increase in fat-free mass with ibutamoren compared to placebo (14)