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C.Agreda-MellonD.LucioJ.Mendes-GianniniM

Nov 15 2018;50:247-256

Understanding mast cells as neuroimmune amplifiers helps explain why many autoimmune brain disorders present with fluctuating, multisystem symptoms neurological, psychiatric, gastrointestinal, and dermatological and why traditional autoimmunity testing often misses key contributors

Samples were subjected to Seahorse analysis (Agilent) as previously described ( 6 cells/mL for the cell lines and 5 10 6 /mL for the primary CLL primary lymphocytes

In contrast, enrichments in human cell gene expression identified substantially fewer inflammatory pathways
