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-Synuclein misfolding and aggregation: implications in Parkinsons disease pathogenesis

Corticosteroids suppress inflammation effectively but don't address underlying tissue damage and can degrade cartilage over repeated use

One of the major obstacles is determining the optimal dosage and treatment duration (Greten and Grivennikov, 2019)

The compound supports recovery at the cellular level by maintaining NAD+ levels, but it cannot overcome chronic overtraining or sleep deprivation