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FI was measured for all surviving mice at baseline (27 months) and every 2 weeks until a final assessment at 30 months (3HAA diet study), or at 12 and 18 months of age ( Haao knockout study) as previously described 68

however, most studies suggest that there is a shortening of telomeres in smokers [311] associated with lipoperoxidation [312]

Physical activity increases tryptophan availability, enhancing serotonin synthesis and neurotransmission [144, 145]

10.1016/j.arr.2012.06.003 160 MarucciG.BuccioniM.BenD

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