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Endocrine Reviews

A phase 3, randomized, controlled trial of resmetirom in NASH with liver fibrosis

Dec 2021;33(12):3269-3274

These discrepancies point to the fact that the activity of gut metabolites and signaling mediators is highly contextdependent, influenced by variables such as dietary inputs, gut microbiota composition, host health status, and metabolic individuality

59 Shafei reported that BCAT1 inhibited the Ras/ERK pathway and activates PI3K/AKT pathway through insulin/IGF-1, ultimately promoting the expression levels of FOXO3a and Nrf2 and regulating the proliferation, migration, and invasion in triple-negative breast cancer (TNBC)